The Vidavii Circuit Meets Psychedelics And Neuroplasticity
The Longevity Salon positions itself as a cross-disciplinary community of practitioners, researchers, and innovators exploring the science of human longevity. Founded by neuroeconomist and psychologist Antonia Schultze-Mosgau and Tim Cook, creator of GEEKfoods, the collaboration brought together expertise in cognition, behaviour, and decision-making with a practical emphasis on nutrition, performance, and metabolic health.
Their recent event, Unlocking Human Potential: The Intersection of Psychedelics, Neuroplasticity & Longevity, was hosted at Vidavii Mayfair – a technology-driven wellness space organised around what it calls a “longevity circuit.” This consists of a sequence of treatments aimed at supporting recovery and physiological regulation, including infrared sauna, cryotherapy, lymphatic drainage, and dry water massage. The setting combines clinical precision with a high-end wellness aesthetic, reflecting a broader shift toward more active, intervention-based approaches within London’s wellbeing landscape.
After welcoming and waking guests with cups of GEEK mushroom coffee and pea protein shakes, the day’s cohort of guinea pigs settled into an introductory deep dive on psychedelic neuroscience, with a panel featuring researchers from Imperial College London’s Centre for Psychedelic Research led by David Nutt, alongside Longevity Architect Michal Cohen-Sagi, who was representing Vidavii’s Circuit of Life and NeuroVIZR. Central to the discussion were the mechanisms by which psychedelics appear to increase neural flexibility – temporarily disrupting entrenched network dynamics and enabling new patterns of activity – and how these shifts may relate to changes in mood, perception, and behaviour.
In animal models psychedelics are understood to increase plasticity structurally (new dendrites and spines), functionally (enhancing cell excitability and long-term potentiation), and behaviourally (increasing cognitive and psychological flexibility). At the molecular level this involves genes encoding for BDNF and components of the mTOR pathway similarly involved in conventional anti-depressants; Structurally, changes mirror those seen during successful learning and memory formation; And on the metaplastic level – neurons may be primed to respond more readily to future plasticity inducing stimuli, creating lasting alterations in neuronal responsiveness.
The conversation extended into therapeutic contexts, particularly depression, anxiety, and stress-related conditions, while also touching on systemic effects beyond the brain, including links to broader physiological regulation. Importantly, it did not treat the concept of “rewiring” as a simple or universally positive process, but as one contingent on context, interpretation, and integration. The session concluded with an open Q&A, where the tensions between evidence and application, or promise and uncertainty were actively probed.
Theory grounded, the afternoon shifted into a more embodied phase with a structured rotation through two complementary experience pathways, designed as a single, integrated journey. In Path A, attendees took part in a longevity-optimised brunch curated by GEEK, drawing on nutritional protocols associated with Dr. Oliver Zolman and popularised by Bryan Johnson. The focus here was on food as intervention – meals formulated to support metabolic efficiency, cellular health, and sustained energy, reframing dining as a component of biological optimisation rather than just consumption.
In parallel Path B, attendees were introduced to an experiential exploration of Vidavii’s circuits, including the NeuroVIZR system – using light and sound to induce altered perceptual states; alongside dry water massage, lymphatic drainage, cryotherapy, and infrared sauna environments with ionised air and aromatherapy. With nutrition as the input and technology as external modulation, the day took a systems-based approach in which multiple variables (metabolic, sensory, and physiological) were adjusted in tandem, offering a practical demonstration of how contemporary longevity culture conceptualises the body as something that can be tuned rather than simply maintained.
Antonia Schultze-Mosgau’s work provides a useful context for understanding the broader aims of the event. Through her involvement with Gowing Life and the Oxford biohacking community, she focuses on how people make decisions about long-term health and why sustained behaviour change is often difficult. Her approach highlights the role of cognitive bias, environment, and habit in shaping health outcomes. In this context, the event reflected not only advances in science and technology, but also the ongoing challenge of translating these into consistent, real-world practice. In this sense, the future of health and longevity depends as much on context, behaviour, and interpretation as it does on molecules, metrics, or machines.
